At Electro-Molecular Discovery (EMD Bio), we deliver innovative spatial multi-omics tools that bridge the gap between tissue architecture and molecular complexity. Our barcode-enabled spatial profiling kits allow simultaneous analysis of gene expression, protein distribution, and metabolic activity at single-cell and subcellular resolution.
What is Spatial Multi-Omics ?
Spatial multi-omics integrates transcriptomics, proteomics, and metabolomics with spatial coordinates inside intact tissue sections. Unlike dissociative single-cell analysis, spatial omics retains cellular localization—allowing researchers to study cell identity, microenvironmental interactions, and disease heterogeneity in situ.
Applications of Spatial Tissue Profiling
- Single-Cell Gene Expression Mapping
Capture transcriptomic signatures in their native tissue context using barcoded capture slides, RNA-seq-compatible workflows, and spatial barcoding technologies.
Source : here
- Spatial Proteomics
Profile protein abundance and post-translational modifications using antibody-oligo conjugates, immunofluorescence panels, and mass spec-compatible tissue imaging.
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- Tissue-Resolved Metabolomics
Visualize metabolic flux and small molecule localization using label-free imaging, laser ablation mass spectrometry, and FRET/metabolic probes.
Learn more : here
- Tumor Microenvironment Deconvolution
Identify immune cells, stromal elements, and malignant clones in spatially organized cancer tissues—ideal for oncology, immunotherapy, and biomarker discovery.
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