In modern neuroscience, protein targeting technologies play a vital role in dissecting the complexity of brain circuits, synaptic signaling, and neuronal connectivity. At Electro-Molecular Discovery (EMD Bio), we offer advanced selective probes, fluorescent antibodies, and tagging systems engineered for reliable and reproducible protein tracking in living and fixed neural tissues.
Why Protein Targeting Matters in Brain Research ?
Neurons communicate through highly organized structures and dynamic protein networks. Understanding these processes requires tools that enable real-time localization, quantification, and modulation of specific proteins, such as:
- Neuropeptides (e.g., oxytocin, vasopressin, substance P)
- Ion channels (e.g., sodium, potassium, calcium channels)
- Neurotransmitter receptors (e.g., GABA, glutamate, dopamine receptors)
With precise targeting, researchers can monitor activity-dependent trafficking, post-translational modifications, and protein-protein interactions in their native context.
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Applications of Protein Targeting in Neuroscience
- Synaptic Vesicle Tracking
Our fluorophore-conjugated antibodies and peptide-based tags allow the live or fixed imaging of proteins involved in neurotransmitter packaging, exocytosis, and synaptic recycling. Common targets include synaptophysin, synapsin, and VAMP proteins.
Learn more : here
- Blood-Brain Barrier (BBB) Permeability Studies
EMD Bio offers small-molecule probes and labeled ligands designed to evaluate BBB transport dynamics and test drug delivery systems that cross the barrier. These tools are crucial for assessing neuroinflammation, gliosis, and neurodegeneration.
Reference : here
- Axon Tracing & Connectivity Mapping
Use targeted tracers and protein tags to trace long-range neuronal projections with spatial and temporal precision. Our offerings include biotinylated, fluorescent, and retrograde transport-compatible tools.
Example: here
