At Electro-Molecular Discovery (EMD Bio), we provide specialized reagents for immune cell profiling and activation studies, enabling high-resolution analysis of the immune landscape in both health and disease. Our portfolio includes fluorophore-conjugated ligands, antibody panels, and activation markers validated for flow cytometry, mass cytometry (CyTOF), and multiplex immunofluorescence.
What is Immune Cell Profiling ?
Immune profiling refers to the identification and quantification of immune cell populations—such as T-cell subsets, B-cells, natural killer (NK) cells, and myeloid cells—based on surface and intracellular markers. It’s essential for understanding immunological responses in oncology, infectious disease, immunotherapy, and vaccine development.
Applications in Immunology Research
- Flow Cytometry Panels
Our pre-optimized panels include monoclonal antibodies conjugated to bright and photostable fluorophores (e.g., Alexa Fluor, PE-Cy7, APC, FITC) for detection of CD3, CD4, CD8, CD19, CD56, CD14, HLA-DR, and more.
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- Mass Cytometry (CyTOF)
Utilize metal-tagged antibodies and isotopically pure reagents for deep profiling of >40 parameters per cell. Ideal for high-dimensional immune analysis in cancer immunology and autoimmune disease studies.
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- Multiplex Immunofluorescence (mIF)
Label immune populations in tissue sections using tyramide signal amplification (TSA) and spectral unmixing for spatial immune mapping in tumors, lymphoid organs, and inflamed tissues.
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- Activation Marker Detection
Track immune cell status with validated antibodies for CD69, CD25, CD38, HLA-DR, PD-1, and ICOS—critical for T-cell activation, exhaustion, and checkpoint analysis.
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